London School of Hygiene & Tropical Medicine AMBITION
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  • Partners
    • London School of Hygiene & Tropical Medicine
    • St. George’s, University of London
    • Liverpool School of Tropical Medicine
    • University of Liverpool
    • Institut Pasteur
    • Botswana-Harvard Partnership
    • University of Zimbabwe
    • Malawi-Liverpool-Wellcome Trust Clinical Research Programme
    • UNC Project Malawi
    • University of Cape Town
    • Infectious Diseases Institute Uganda
  • Work Packages
    • Work Package 1: Clinical Trial
      • Clinical WPDs
      • Laboratory WPDs
      • Trial Management WPDs
    • Work Package 2: Economic Sub-studies
    • Work Package 3: Scientific Sub-studies
      • PK/PD Analysis
      • STOP-CM
      • CrAg Testing
      • Quantitative PCR
      • LEOPARD
    • Work Package 4: African Meningitis Trials Network Development
    • Work Package 5: Training & Capacity Building
      • MSc Scholarships
      • PhD Studentship
      • Training and Capacity Building Events
        • Health Economics Course
        • GCP & Clinical Trials Course
        • Medical Mycology Course
    • Work Package 6: Financial & Administrative Project Management
  • Site Visits
    • Uganda (20-29 January 2020)
  • A Day in the Life
    • Refilwe Mmipi, BHP
  • News
    • Newsletters
  • Contact

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USEFUL LINKS

AMBITION Electronic Data Capture Tool (EDC): Dr. David Lawrence’s YouTube Channel

AMBITION Protocol Version 2.2

ISRCTN Registry (AMBITION-cm)

The International Society for Neglected Tropical Diseases

International Society for Human and Animal Mycology

WHO: Meningitis

EDCTP and Horizon 2020

Horizon 2020 Annotated Model Grant Agreement

PUBLICATIONS

November 2020: Moeng et al (HIV-associated Cryptococcal Meningitis: A Review of Novel Short Course and Oral Therapies)

November 2020: Lawrence and Hirsch (Decolonising global health: transnational research partnerships under the spotlight)

October 2020: Kelentse et al (Differences in HIV-1C Viral Load and Drug Resistance Mutation between Plasma and Cerebrospinal Fluid in Patients with HIV-associated Cryptococcal Meningitis in Botswana)

September 2020: Leeme et al (Utility of CD4 count measurement in the era of universal antiretroviral therapy: an analysis of routine laboratory data in Botswana)

July 2020: Alufandika et al (A pragmatic approach to managing antiretroviral therapy-experienced patients diagnosed with HIV-associated cryptococcal meningitis: impact of antiretroviral therapy adherence and duration)

June 2020: Greene et al (Cryptococcal meningitis: a review of novel cryptococcal antigen screening programs in Africa. Expert Review of Anti-infective Therapy)

May 2020: Lebelonyane et al (Advanced HIV disease in the Botswana Combination Prevention Project: Prevalence, Risk Factors, and Outcomes)

May 2020: Jarvis et al (Evaluation of a Novel Semi-quantitative Cryptococcal Antigen Lateral Flow Assay in Patients with Advanced HIV Disease)

May 2020: Tenforde et al (Outcomes of reflex cryptococcal antigen (CrAg) screening in HIV-positive patients with CD4 counts of 100-200 cells/µL in Botswana)

January 2020: Tenforde et al (Mortality from HIV-associated meningitis in sub-Saharan Africa: a systematic review and meta-analysis)

April 2019: Ponatshego et al (High dose AmBisome for cryptococcal meningitis induction therapy in sub-Saharan Africa: economic evaluation protocol for a randomised controlled trial-based equivalence study)

October 2018: Lawrence et al (AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non-Inferiority Trial)

Contact Us

London School of Hygiene & Tropical Medicine
Keppel Street, London WC1E 7HT, UK

About Us

This project has received funding from the European Union’s Horizon 2020 research and innovation programme under Grant Agreement Number TRIA2015-1092.

This project is part of the EDCTP2 programme supported by the European Union.

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Keppel Street, London WC1E 7HT, UK

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