{"id":9497,"date":"2024-12-09T10:55:31","date_gmt":"2024-12-09T10:55:31","guid":{"rendered":"https:\/\/blogs.lshtm.ac.uk\/iceh-new\/?page_id=9497"},"modified":"2025-12-04T16:37:53","modified_gmt":"2025-12-04T16:37:53","slug":"the-earn-trial","status":"publish","type":"page","link":"https:\/\/blogs.lshtm.ac.uk\/iceh-new\/the-earn-trial\/","title":{"rendered":"The EARN Trial"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;section&#8221; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;39px||2px|||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; custom_margin=&#8221;-13px|auto||auto||&#8221; custom_padding=&#8221;12px|||||&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.18.0&#8243; text_font=&#8221;||||||||&#8221; header_font=&#8221;Roboto||||||||&#8221; header_text_color=&#8221;#323232&#8243; header_font_size=&#8221;40px&#8221; header_line_height=&#8221;1.2em&#8221; max_width=&#8221;85%&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;||19px|||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h1 style=\"text-align: left\"><strong>The EARN Trial\u00a0<\/strong><\/h1>\n<p>[\/et_pb_text][et_pb_divider color=&#8221;#003389&#8243; divider_weight=&#8221;3px&#8221; _builder_version=&#8221;4.16&#8243; width=&#8221;100%&#8221; max_width=&#8221;21%&#8221; module_alignment=&#8221;left&#8221; custom_margin=&#8221;|||0px|false|false&#8221; custom_padding=&#8221;|||80px|false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][et_pb_image src=&#8221;https:\/\/blogs.lshtm.ac.uk\/iceh-new\/files\/2025\/03\/Untitled-design-30.png&#8221; alt=&#8221;In India, a woman tries on glasses while sewing&#8221; title_text=&#8221;Untitled design (30)&#8221; align=&#8221;center&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; width=&#8221;85%&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;475.1px&#8221; custom_margin=&#8221;-20px||||false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_text _builder_version=&#8221;4.27.4&#8243; text_font=&#8221;|600|||||||&#8221; text_text_color=&#8221;#323232&#8243; text_font_size=&#8221;16px&#8221; link_text_color=&#8221;#3344dd&#8221; header_font=&#8221;Roboto||||||||&#8221; header_text_color=&#8221;#323232&#8243; header_2_font_size=&#8221;18px&#8221; header_3_font_size=&#8221;14px&#8221; max_width=&#8221;85%&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;88px&#8221; custom_margin=&#8221;-8px||25px||false|false&#8221; custom_padding=&#8221;0px||0px|||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2><strong>Background<\/strong><\/h2>\n<p>Presbyopia, the age-related loss of near vision, affects over 1 billion people worldwide, typically beginning around age 40. It results from the eye\u2019s lens losing flexibility, making it difficult to focus on close objects. Left uncorrected, presbyopia can hinder daily tasks such as reading, using digital devices, and performing work that requires precision, which impacts quality of life and productivity.<\/p>\n<p>The burden of presbyopia is particularly severe in low- and middle-income countries (LMICs), where access to affordable corrective solutions is limited. Many individuals cannot afford or access simple reading glasses, leaving them unable to work or engage fully in their communities. This exacerbates social and economic inequalities.<\/p>\n<p>Globally, an estimated 800 million people need reading glasses but do not have them.<\/p>\n<p>&nbsp;<\/p>\n<h2><strong>The Trial<\/strong><\/h2>\n<p>A $4.8m grant, contributed by <a href=\"https:\/\/www.givewell.org\/about\">GiveWell<\/a> and the <a href=\"https:\/\/www.livelihoodimpactfund.org\/\">Livelihood Impact Fund<\/a>, will be used to assess the impact of providing eyeglasses for people with near-vision impairments in India and Kenya.<\/p>\n<p>The randomised controlled trial of the Economic Advantages of Readers for Near vision (EARN), will test the effect on income, household consumption and expenditure, and vision-related quality of life for adults 35-65, before and after being provided with glasses.<\/p>\n<p>The trial will also look at other economic and quality-of-life metrics for participants, such as self-reported productivity and general health-related quality of life.<\/p>\n<p>Our partners for the project are Dr Shroff\u2019s Charity Eye Hospital in India, and Kenya Medical Research Institute in Kenya, who are both long-term collaborators with ICEH.<\/p>\n<p>Starting in 2024 and running for five years, it\u2019s hoped that the trial results will provide evidence that supplying people with near-vision spectacles is a cost-effective mechanism for development, improving lives and livelihoods for individuals, families and communities.<\/p>\n<p>Long term, this could potentially lead to more funding for the provision of reading glasses, using eye health to unlock progress in low and middle-income countries globally.<\/p>\n<p>[\/et_pb_text][et_pb_slider _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; width=&#8221;85%&#8221; module_alignment=&#8221;center&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_slide heading=&#8221;EARN infographic&#8221; button_text=&#8221;Download &#8221; button_link=&#8221;https:\/\/blogs.lshtm.ac.uk\/iceh-new\/files\/2025\/11\/EARN-Infographic_Funders.pdf&#8221; url_new_window=&#8221;on&#8221; image=&#8221;https:\/\/blogs.lshtm.ac.uk\/iceh-new\/files\/2025\/10\/1.png&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; header_font=&#8221;Oswald|500|||||||&#8221; background_color=&#8221;#003389&#8243; background_enable_color=&#8221;on&#8221; custom_button=&#8221;on&#8221; button_text_color=&#8221;#003389&#8243; button_bg_color=&#8221;#ffffff&#8221; button_font=&#8221;|600|||||||&#8221; global_colors_info=&#8221;{}&#8221; sticky_transition=&#8221;on&#8221;]<\/p>\n<p>Access an infographic on the EARN trial and its aims.<\/p>\n<p>[\/et_pb_slide][\/et_pb_slider][et_pb_text _builder_version=&#8221;4.27.4&#8243; text_font=&#8221;|600|||||||&#8221; text_text_color=&#8221;#323232&#8243; text_font_size=&#8221;16px&#8221; link_text_color=&#8221;#3344dd&#8221; header_font=&#8221;Roboto||||||||&#8221; header_text_color=&#8221;#323232&#8243; header_2_font_size=&#8221;18px&#8221; header_3_font_size=&#8221;14px&#8221; max_width=&#8221;85%&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;88px&#8221; custom_margin=&#8221;2px||15px||false|false&#8221; custom_padding=&#8221;0px||0px|||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2><strong>Details<\/strong><\/h2>\n<p><span style=\"text-decoration: underline\">Location:<\/span> India &amp; Kenya<\/p>\n<p><span style=\"text-decoration: underline\">Design:<\/span> Two prospective, single-masked, parallel group, two-arm individually randomised controlled trials (RCTs)<\/p>\n<p><span style=\"text-decoration: underline\">Primary objectives:<\/span> To determine if the provision of near vision glasses to people of working age with presbyopia leads to increased household consumption and\/or vision related quality of life.<\/p>\n<p><span style=\"text-decoration: underline\">Secondary objectives:<\/span> To determine if the provision of near vision glasses to people of working age with presbyopia leads to: (i) increased individual income; (ii) increased household consumption, individual income, and\/or workplace productivity in those who work in near vision intense\/dependent occupations (occupational sub-group analysis).<\/p>\n<p><span style=\"text-decoration: underline\">Co-primary outcomes:<\/span><br \/>\u2022 Household consumption at 12 months and vision related quality of life at 12 months<\/p>\n<p><span style=\"text-decoration: underline\">Secondary outcomes:<\/span><br \/>\u2022 Employment status and characteristics<br \/>\u2022 Self-reported productivity (presenteeism and absenteeism)<br \/>\u2022 Self-reported income sufficiency<br \/>\u2022 Self-reported individual income<br \/>\u2022 Health Related Quality of Life: EQ5D with vision bolt-on question.<\/p>\n<p><span style=\"text-decoration: underline\">Participants:<\/span> Individuals with presbyopia (&lt;N8) identified through established screening programmes, who meet the trial inclusion criteria.<\/p>\n<p><span style=\"text-decoration: underline\">Intervention:<\/span> Trial participants will be randomised to one of the following arms:<br \/>\u2022 Intervention arm: individuals will be given free near vision glasses (spherical, non-astigmatic correction), appropriate for their degree of presbyopia. As they are given glasses they will be counselled about the use and care of the glasses.<br \/>\u2022 Control arm: individuals will not be given free near vision glasses at baseline. They will be given free near vision glasses (spherical, non-astigmatic correction), appropriate for their degree of presbyopia at the end of the trial follow-up period (2 years). However, they will be informed that they have presbyopia at baseline, so it is possible that some may choose to independently purchase glasses themselves.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The EARN Trial\u00a0Background Presbyopia, the age-related loss of near vision, affects over 1 billion people worldwide, typically beginning around age 40. It results from the eye\u2019s lens losing flexibility, making it difficult to focus on close objects. Left uncorrected, presbyopia can hinder daily tasks such as reading, using digital devices, and performing work that requires [&hellip;]<\/p>\n","protected":false},"author":845,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-9497","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>The EARN Trial - ICEH<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.lshtm.ac.uk\/iceh-new\/the-earn-trial\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The EARN Trial - ICEH\" \/>\n<meta property=\"og:description\" content=\"The EARN Trial\u00a0Background Presbyopia, the age-related loss of near vision, affects over 1 billion people worldwide, typically beginning around age 40. 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