{"id":5064,"date":"2018-05-28T13:38:30","date_gmt":"2018-05-28T13:38:30","guid":{"rendered":"http:\/\/blogs.lshtm.ac.uk\/library\/?p=5064"},"modified":"2018-05-28T14:49:04","modified_gmt":"2018-05-28T14:49:04","slug":"books-on-clinical-trials","status":"publish","type":"post","link":"https:\/\/blogs.lshtm.ac.uk\/library\/2018\/05\/28\/books-on-clinical-trials\/","title":{"rendered":"Books on Clinical Trials"},"content":{"rendered":"<p>May 20th was International Clinical Trials Day. The very first clinical trial occurred back in 1747 when naval surgeon-mate James Lind determined that scurvy could be successfully reversed by eating citrus fruit. Nowadays the randomized clinical trial is regarded as fundamental to evidence-based medicine.<\/p>\n<p>At LSHTM library, most books about clinical trials are classified at\u00a0classmark <strong>EHB<\/strong>, with some books at other classmarks and several texts available as <strong>ebooks<\/strong>.<\/p>\n<p>Here are a few items from the collection.<\/p>\n<hr \/>\n<h3>General works<\/h3>\n<p><strong><a href=\"http:\/\/blogs.lshtm.ac.uk\/library\/files\/2018\/05\/5119EGTTG4L._SX358_BO1204203200_.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-5101\" src=\"http:\/\/blogs.lshtm.ac.uk\/library\/files\/2018\/05\/5119EGTTG4L._SX358_BO1204203200_-216x300.jpg\" alt=\"Clinical Trials: A Practical Guide to Design, Analysis, and Reporting\u00a0by\u00a0Duolao Wang and\u00a0Ameet Bakhai \" width=\"200\" height=\"277\" srcset=\"https:\/\/blogs.lshtm.ac.uk\/library\/files\/2018\/05\/5119EGTTG4L._SX358_BO1204203200_-216x300.jpg 216w, https:\/\/blogs.lshtm.ac.uk\/library\/files\/2018\/05\/5119EGTTG4L._SX358_BO1204203200_.jpg 360w\" sizes=\"auto, (max-width: 200px) 100vw, 200px\" \/><\/a>Clinical Trials: A Practical Guide to Design, Analysis, and Reporting<\/strong>\u00a0by\u00a0Duolao Wang and\u00a0Ameet Bakhai (Remedica, 2006)<\/p>\n<p>Library classmark: <strong>EHB 2006<\/strong><\/p>\n<p>Explains the basics of conducting clinical trials in a clear and systematic way, with plenty of\u00a0illustrative examples from real-life trials. Set out in short chapters within five sections covering fundamentals of trial design, alternative trial designs, basics of statistical analysis, special trial issues in data analysis, and reporting of trials.<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"http:\/\/blogs.lshtm.ac.uk\/library\/files\/2018\/05\/Textbook-Machin-2004.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-5114\" src=\"http:\/\/blogs.lshtm.ac.uk\/library\/files\/2018\/05\/Textbook-Machin-2004-231x300.jpg\" alt=\"Textbook of Clinical Trials Machin 2004\" width=\"200\" height=\"260\" srcset=\"https:\/\/blogs.lshtm.ac.uk\/library\/files\/2018\/05\/Textbook-Machin-2004-231x300.jpg 231w, https:\/\/blogs.lshtm.ac.uk\/library\/files\/2018\/05\/Textbook-Machin-2004.jpg 384w\" sizes=\"auto, (max-width: 200px) 100vw, 200px\" \/><\/a><strong>Textbook of Clinical Trials<\/strong> edited by David Machin, Simon Day and Sylvan Green (Wiley, 2004)<\/p>\n<p>Library classmark: <strong>EHB 2004<\/strong><\/p>\n<p>A comprehensive work describing the impact and development of clinical trials and medical statistics. Information is organised in sections specific to cancer, cardiovascular disease, dentistry, dermatology, psychiatry, reproductive health and respiratory disease.<\/p>\n<p>&nbsp;<\/p>\n<hr \/>\n<h3>Specialised topics<\/h3>\n<p><strong><a href=\"http:\/\/blogs.lshtm.ac.uk\/library\/files\/2018\/05\/Field-Trials-Smith-2015.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-5128\" src=\"http:\/\/blogs.lshtm.ac.uk\/library\/files\/2018\/05\/Field-Trials-Smith-2015.jpg\" alt=\"Field Trials of Health Interventions Smith 2015\" width=\"200\" height=\"300\" \/><\/a>Field Trials of Health Interventions: A Toolbox<\/strong> by\u00a0Peter G. Smith, Richard H. Morrow, David A. Ross (OUP, 2015)<\/p>\n<p>Library classmark: <strong>UB 2015\u00a0<\/strong><\/p>\n<p>Also <a href=\"http:\/\/oapen.org\/view?docId=569923.TOC.nxml\">available online<\/a><\/p>\n<p><span class=\"p\">This is a practical guide to conducting trials in low- and middle-income countries with\u00a0participants in their normal environments rather than in clinical settings. The main emphasis is on randomized controlled trials. The book aims to help new investigators build on the experience of others rather than repeating their mistakes.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"http:\/\/blogs.lshtm.ac.uk\/library\/files\/2018\/05\/Rosenberger-2016.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-5109\" src=\"http:\/\/blogs.lshtm.ac.uk\/library\/files\/2018\/05\/Rosenberger-2016.jpg\" alt=\"Randomization in Clinical Trials Rosenberger 2016\" width=\"200\" height=\"282\" \/><\/a><\/p>\n<p><strong>Randomization in Clinical Trials: Theory and Practice<\/strong> (2nd ed.) by William F. Rosenberger and John M. Lachin (Wiley, 2016)<\/p>\n<p>Library classmark: <strong>EHB 2016<\/strong><\/p>\n<p>This reference for researchers, applied statisticians and biostatisticians discusses\u00a0current philosophies, controversies and new developments with the role of randomization techniques in clinical trials. \u00a0Includes\u00a0problem sets, theoretical exercises and computer simulations.<\/p>\n<p>&nbsp;<\/p>\n<p class=\"a-size-medium s-inline s-access-title a-text-normal\"><strong><a href=\"http:\/\/blogs.lshtm.ac.uk\/library\/files\/2018\/05\/Fayers-QoL-2005.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-5094 alignright\" src=\"http:\/\/blogs.lshtm.ac.uk\/library\/files\/2018\/05\/Fayers-QoL-2005.jpg\" alt=\"Assessing quality of life in clinical trials by Fayers 2005\" width=\"200\" height=\"289\" \/><\/a>Assessing Quality of Life in Clinical Trials: Methods and Practice<\/strong> (2nd ed.) edited by Peter Fayers and Ron Hays (OUP, 2005)<\/p>\n<p>Library classmark: <strong>EHB.AT 2005<\/strong><\/p>\n<p>Quality of life is an important outcome measure in longitudinal research but presents challenges for the researcher in terms of methodology. This book offers innovative and practical approaches to the design and evaluation of patient-reported outcomes assessments.<\/p>\n<p>&nbsp;<\/p>\n<p><strong><a href=\"http:\/\/blogs.lshtm.ac.uk\/library\/files\/2018\/05\/Missing-Data-Michael-OKelly.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-5096\" src=\"http:\/\/blogs.lshtm.ac.uk\/library\/files\/2018\/05\/Missing-Data-Michael-OKelly.jpg\" alt=\"Clinical Trials with Missing Data Michael O'Kelly and Bohdana Ratitch (Wiley 2014)\" width=\"200\" height=\"311\" srcset=\"https:\/\/blogs.lshtm.ac.uk\/library\/files\/2018\/05\/Missing-Data-Michael-OKelly.jpg 321w, https:\/\/blogs.lshtm.ac.uk\/library\/files\/2018\/05\/Missing-Data-Michael-OKelly-193x300.jpg 193w\" sizes=\"auto, (max-width: 200px) 100vw, 200px\" \/><\/a>Clinical Trials with Missing Data<\/strong>\u00a0by Michael O&#8217;Kelly and Bohdana Ratitch (Wiley 2014)<\/p>\n<p>Library classmark: <strong>EHB 2014<\/strong><\/p>\n<p>This volume describe how missing data can affect the outcome and credibility of a clinical trial. It discusses the ways in which a clinical team can work to minimise the occurrence of missing data, and how the problem can be effectively addressed when it does occur. Case studies, worked examples and clear guidelines are provided throughout.<\/p>\n<p>&nbsp;<\/p>\n<hr \/>\n<h3>One author with a book for beginners and a book for experts.<\/h3>\n<p><a href=\"http:\/\/blogs.lshtm.ac.uk\/library\/files\/2018\/05\/Meinart_2011.jpg\"><img loading=\"lazy\" decoding=\"async\" width=\"200\" height=\"300\" class=\"alignright size-medium wp-image-5070\" src=\"http:\/\/blogs.lshtm.ac.uk\/library\/files\/2018\/05\/Meinart_2011-200x300.jpg\" alt=\"An Insider's Guide to Clinical Trials by Curtis L. Meinert. OUP, 2011.\" srcset=\"https:\/\/blogs.lshtm.ac.uk\/library\/files\/2018\/05\/Meinart_2011-200x300.jpg 200w, https:\/\/blogs.lshtm.ac.uk\/library\/files\/2018\/05\/Meinart_2011.jpg 333w\" sizes=\"auto, (max-width: 200px) 100vw, 200px\" \/><\/a><strong>An Insider&#8217;s Guide to Clinical Trials<\/strong> by Curtis L. Meinert (OUP, 2011).<\/p>\n<p>Library classmark: <strong>EHB 2011<\/strong><\/p>\n<p>Also <a href=\"https:\/\/www.dawsonera.com\/abstract\/9780199876655\">available online<\/a><\/p>\n<p>Aimed at students and people without a background in the field, this is a conversational book explaining how trials are designed and run, who and what gets studied, how trials are reported and how to interpret the results. Includes sections on authorship credit, ethics, research misconduct, research myths, and a &#8220;shopping for a trial&#8221; section for those interested in participating as a subject.<\/p>\n<p>&nbsp;<\/p>\n<p><strong><a href=\"http:\/\/blogs.lshtm.ac.uk\/library\/files\/2018\/05\/Clinical-Trials-Design-Conduct-Analysis-by-Meinert-2012-1.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-5122\" src=\"http:\/\/blogs.lshtm.ac.uk\/library\/files\/2018\/05\/Clinical-Trials-Design-Conduct-Analysis-by-Meinert-2012-1.jpg\" alt=\"Clinical Trials Design Conduct Analysis by Meinert 2012\" width=\"200\" height=\"270\" \/><\/a>Clinical Trials: Design, Conduct, and Analysis<\/strong> (2nd ed.) by Curtis L. Meinert (OUP 2012)<\/p>\n<p>Library classmark: <strong>EHB 2012<\/strong><\/p>\n<p>An authoritative text full of practical instruction along with tables, checklists, charts and other resources. The very detailed information is grouped into eight broad areas including design principles and practices, execution, data analysis, organisation and management, and publication.<\/p>\n<p>&nbsp;<\/p>\n<hr \/>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>May 20th was International Clinical Trials Day. The very first clinical trial occurred back in&#8230;<\/p>\n","protected":false},"author":449,"featured_media":5088,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7575,27710],"tags":[],"class_list":["post-5064","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-books","category-library-resources","odd"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Books on Clinical Trials - Library, Archive &amp; Open Research Services blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.lshtm.ac.uk\/library\/2018\/05\/28\/books-on-clinical-trials\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Books on Clinical Trials - Library, Archive &amp; Open Research Services blog\" \/>\n<meta property=\"og:description\" content=\"May 20th was International Clinical Trials Day. 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