Trachomatous Trichiasis – Disease and Management

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Trachomatous Trichiasis – Disease and Management

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We have been working on several aspects of the management of trichiasis: improving the long-term outcome of eyelid surgery, the optimal treatment for the earlier stages of the disease and detailed studies on the clinical features of the disease. This has included five large clinical trials that have explored the use of postoperative azithromycin, alternative suture materials, the role of epilation in mild disease and a comparison of different operation types and the use of postoperative doxycycline.

Oral doxycycline after surgery for trachomatous trichiasis in Ethiopia: a randomised, double-blind, placebo-controlled trial.

E.Habtamu, T.Wondie, S.Aweke, Z.Tadesse, M.Zerihun, B.Gashaw, C.h.Roberts, A.B.Kello, D.C.W.Mabey, S.N.Rajak, E.K.Callahan, D.Macleod, H.A.Weiss and M.J.Burton

Lancet Global Health, 2018, 6:e579-e592

Posterior versus bilamellar tarsal rotation surgery for trachomatous trichiasis in Ethiopia: a randomised controlled trial

E.Habtamu, T.Wondie, S.Aweke, Z.Tadesse,  M.Zerihun, Z.Zewudie, A.B.Kello, C.h.Roberts, P.M.Emerson, R.L.Bailey, D.C.W.Mabey, S.N.Rajak, K.Callahan, H.A.Weiss and M.J.Burton

Lancet Global Health, 2016, 4(3): e175-184

Absorbable versus silk sutures for surgical treatment of trachomatous trichiasis in Ethiopia: A randomised controlled trial

S.N.Rajak, E.Habtamu, H.A.Weiss, A.B.Kello, T.Gebre, A.Genet, R.L.Bailey, D.C.W.Mabey, P.T.Khaw, C.E.Gilbert, P.M.Emerson and M.J.Burton

PLoS Medicine, 2011; 8(12): e1001137

Surgery versus epilation for the treatment of minor trichiasis in Ethiopia: a randomised controlled non-inferiority trial

S.N.Rajak, E.Habtamu, H.A.Weiss, A.B.Kello, T.Gebre, A.Genet, R.L.Bailey, D.C.W.Mabey, P.T.Khaw, C.E.Gilbert, P.M.Emerson and M.J.Burton

PLoS Medicine, 2011; 8(12): e1001136

A randomised controlled trial of azithromycin following surgery for trachomatous trichiasis in The Gambia. 

M.J.Burton, F.Kinteh, O.Jallow, A.Sillah, M.Bah, M.Faye, E.A.N.Aryee, U.N.Ikumapayi, N.D.E.Alexander, R.A.Adegbola, H.Faal, D.C.W.Mabey, A.Foster, G.J.Johnson and R.L.Bailey.

British Journal of Ophthalmology, 2005; 89: 1282-1288

Effect of repeated epilation for minor trachomatous trichiasis on lash burden, phenotype, and surgical management willingness: a cohort study.

Esmael Habtamu, Tariku Wondie, Wubshet Gobezie, Zerihun Tadesse, Bizuayehu Gashaw, Abebaw Gebeyehu, Chrissy h Roberts, E. Kelly Callahan, David Macleod, and Matthew J. Burton

PLOS Neglected Tropical Diseases, 2020, In Pressv

Posterior lamellar versus bilamellar tarsal rotation surgery for trachomatous trichiasis: long-term outcomes from a randomised controlled trial.

E.Habtamu, T.Wondie, Z.Tadesse, B.Atinafu, B.Gashaw, A.Gebeyehu, E.K.Callahan, D.Macleod, and M.J.Burton

EClinicalMedicine, 2019, In Press.

Pre-operative Trichiatic Eyelash Pattern Predicts Post-operative Trachomatous Trichiasis

E.W.Gower, B.Munoz, S.Rajak, E.Habtamu, S.K.West, S.L.Merbs, E.K.Callahan and M.J.Burton

PLOS Neglected Tropical Diseases, 2019, 13(10):e0007637

Impact of trichiasis surgery on daily living: A longitudinal study in Ethiopia

E.Habtamu, T.Wondie, S.Aweke, Z.Tadesse, M.Zerihun, B.Melak, B.Gashaw, K.Callahan, P.M.Emerson, R.L.Bailey, D.C.W.Mabey, S.N.Rajak, H.Kuper, S.Polack, D.Macleod, H.A.Weiss and M.J.Burton

Wellcome Open Research, 2017, 2:69

Predictors of Trachomatous Trichiasis Surgery Outcome

E.Habtamu, T.Wondie, S.Aweke, Z.Tadesse, M.Zerihun, B.Gashaw, G.S.Wondimagegn, H.D.Mengistie, S. N.Rajak, K.Callahan, H.A.Weiss, and M.J.Burton

Ophthalmology, 2017, 114(8):1143-1155

Impact of Trichiasis Surgery on Quality of Life: a longitudinal study in Ethiopia

E.Habtamu, T.Wondie, S.Aweke, Z.Tadesse, M.Zerihun, Z.Zewdie, K.Callahan, P.M.Emerson, H.Kuper, R.L.Bailey, D.C.W.Mabey, S.N.Rajak, S.Polack, H.A.Weiss and M.J.Burton

PLOS Neglected Tropical Diseases, 2016, 10(4):e0004627

The impact of Trachomatous Trichiasis on Quality of Life: a case-control study 

E.Habtamu, T.Wondie, S.Aweke, Z.Tadesse, M.Zerihun, Z.Zewdie, K.Callahan, P.M.Emerson,  H.Kuper, R.L.Bailey, D.C.W.Mabey, S.N.Rajak, S.Polack, H.A.Weiss and M.J.Burton

PLOS Neglected Tropical Diseases, 2015, 9(11):e0004254

Trachoma and Relative Poverty: a case-control study 

E.Habtamu, T.Wondie, S.Aweke, Z.Tadesse, M.Zerihun, Z.Zewdie, K.Callahan, P.M.Emerson,  H.Kuper, R.L.Bailey, D.C.W.Mabey, S.N.Rajak, S.Polack, H.A.Weiss and M.J.Burton

PLOS Neglected Tropical Diseases, 2015, 9(11):e0004228

Epilation for minor trachomatous trichiasis: four-year results of a randomised controlled trial

E.Habtamu, S.N.Rajak, Z.Tadesse, T.Wondie, M.Zerihun, B.Guadie, T.Gebre, A.B.Kello, K.Callahan, D.C.W.Mabey, P.T.Khaw, C.E.Gilbert, H.A.Weiss, P.M.Emerson and M.J.Burton

PLOS Neglected Tropical Diseases, 2015; 13;9(3):e0003558

Trachomatous trichiasis and its management in endemic countries

S.N.Rajak, J.R.O.Collin and M.J.Burton

Survey of Ophthalmology, 2012; 57(2):105-35

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