Author Archives: Sam Alsford

Amino acid transport and drug efficacy

Back in 2012, we published our study decoding the anti-T. brucei drug efficacy determinants – or parasite proteins critical to drug action, such as drug transporters and activators. This identified a slew of proteins that drive the action of the … Continue reading

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Welcoming Juan Macedo to the lab

Dr Juan Macedo joined the lab on the 7th March, supported by a Swiss National Science Foundation early mobility post-doctoral fellowship. Juan has spent the last few years at the University of Bern working with Peter Butikofer and Doris Rentsch … Continue reading

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The 34th annual SwissTryp meeting in Leysin

Thanks to Pascal Maser (SwissTPH) for inviting me to present our latest apoL1 and anti-leishmanial drug RNAi library findings at the 2017 SwissTryp meeting in Leysin, Switzerland (11th-13th January, 2017). It was a great opportunity to hear about some of the … Continue reading

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Old projects come to fruition in 2016

After leaving David Horn’s lab almost four years ago in August 2013, when David and his group moved to the University of Dundee, we’re still managing to publish papers together. That’s the consequence of spending ten years in the same small but … Continue reading

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Ubiquitination influences suramin efficacy

Suramin is one of the oldest drugs still in use today – it’s been used to treat early stage human African trypanosomiasis caused by T. b. rhodesiense since the early 1920s. Back in 2012 we showed that suramin uptake was dependent on … Continue reading

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DELTAS programme at WACCBIP, University of Ghana

On the 12th/13th November the WACCBIP DELTAS programme inception meeting took place in the Biochemistry, Cell & Molecular Biology department at the University of Ghana, Accra. This five year programme led by Dr Gordon A. Awandare is funded by the … Continue reading

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Royal Society Pfizer Awards, 19th October 2015

For ten years, the Royal Society-Pfizer Awards have been recognising outstanding African Scientists. For the first time this year, on the 19th October, there were two awardees. The advanced award was presented to Prof Jean-Jacques Muyembe-Tamfum, Institut National de Recherche Biomedicale … Continue reading

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Invited talk at the Institut Pasteur

Jumped on to the Eurostar to Paris on the 7th October and visited the Institut Pasteur on the 8th October to give a seminar (‘Decoding toxin-parasite interactions in Trypanosomatids‘). Thanks to Philippe Bastin and Gerald Späth for hosting (and for … Continue reading

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Talking Microbes with year 6 @ Kingsgate Pimary

The 20th and 24th November saw me talk about microbes to two year 6 classes at Kingsgate Primary School in West Hampstead. They were a fantastically enthusiastic group with loads of great questions, so much so that two 30 minute … Continue reading

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Invited talk at UCL

20th October was spent at University College London (just up the road!) presenting data from our various T. brucei RNAi library screens – something a bit diferent for all the virologists who work in the Division of Infection & Immunity … Continue reading

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