Alsford Lab

Research

Work in the lab focuses on two aspects of trypanosomatid biology.

1. The uptake and sub-cellular transit of host- and parasite-derived molecules, including nutrients, drugs and innate immune factors.
2. The regulation of RNA polymerase-I transcription, specifically rRNA transcription and its intersection with VSG transcription (and antigenic variation) in Trypanosoma brucei.

Work in the lab is underpinned by our bespoke cell lines & plasmids (all freely available to the research community on request), and our RNAi library and RIT-seq (see Nature Protocols).

Further information on publications and educational activities can be found on my LSHTM Elements page.

|  Lab420, LSHTM, Keppel Street, London WC1E 7HT (find us on Google Maps)

|  Department of Infection Biology  |  Infectious & Tropical Diseases  |  LSHTM