Category Archives: Publication

Why Trypanosoma brucei is sensitive to human serum

Cathepsin-L can resist lysis by human serum in Trypanosoma brucei brucei. PLoS Pathogens 10: e1004130 Featured at: LSHTM, Wellcome Trust See also: commentary in Microbial Cell 1:270-2 Most African trypanosomes, including the veterinary species Trypanosoma brucei brucei and T. congolense (causative agents of the … Continue reading

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Review published in ‘Parasitology’…

Genetic dissection of drug resistance in trypanosomes | Full Text Part of a special edition of Parasitology, 140(12):  Genetic and genomic approaches to understanding drug resistance in parasites (October, 2013). Our understanding of the routes to drug resistance in trypanosomes, … Continue reading

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Latest work on histone chaperones and VSG ES regulation published in Nucleic Acids Research.

Cell-cycle-regulated control of VSG expression site silencing by histones and histone chaperones ASF1A and CAF-1b in Trypanosoma brucei. Nucleic Acids Res. (PubMed | PDF) A longstanding mystery in T. brucei biology is how these parasites are able to express a … Continue reading

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