With the recent lifting of COVID19 restrictions, Matt Rogers and I were finally able to run our two-day summer research experience workshop for the first time since 2018!
On 28th and 29th June we joined by three groups of enthusiastic Y11 and Y12 students and their teachers from St…
After a couple of months on BioRxiv our first pre-print has been accepted for publication in Antimicrobial Agents & Chemotherapy!
‘Chemogenomic profiling of anti-leishmanial efficacy and resistance in the related kinetoplastid parasite Trypanosoma brucei’
Selecting our T. brucei RNAi library in the anti-HAT drugs revolutionised our understanding…
Matt Rogers and I ran our annual research workshop for first-year A-level students on 28-29th June. This time students from St Thomas the Apostle School and 6th Form College joined fellow students from Dulwich College.
All told, we had 15 enthusiastic students in the lab for two…
Juan, Aboagye and I spent several days on Welsh coast at the British Society for Parasitology’s spring meeting in Aberystwyth. Not the easiest place to get to from London, but definitely worth it – a nice location and a great meeting. It was good to be able to present our…
Back in 2012, we published our study decoding the anti-T. brucei drug efficacy determinants – or parasite proteins critical to drug action, such as drug transporters and activators. This identified a slew of proteins that drive the action of the five anti-HAT drugs. More recently, we’ve been following…
Dr Juan Macedo joined the lab on the 7th March, supported by a Swiss National Science Foundation early mobility post-doctoral fellowship.
Juan has spent the last few years at the University of Bern working with Peter Butikofer and Doris Rentsch on T. brucei biochemistry and amino acid transport. After…
Thanks to Pascal Maser (SwissTPH) for inviting me to present our latest apoL1 and anti-leishmanial drug RNAi library findings at the 2017 SwissTryp meeting in Leysin, Switzerland (11th-13th January, 2017). It was a great opportunity to hear about some of the great trypanosomatid research going on in Switzerland…
After leaving David Horn’s lab almost four years ago in August 2013, when David and his group moved to the University of Dundee, we’re still managing to publish papers together. That’s the consequence of spending ten years in the same small but very productive group that also…
Suramin is one of the oldest drugs still in use today – it’s been used to treat early stage human African trypanosomiasis caused by T. b. rhodesiense since the early 1920s. Back in 2012 we showed that suramin uptake was dependent on receptor mediated endocytosis and relied on a complex…
On the 12th/13th November the WACCBIP DELTAS programme inception meeting took place in the Biochemistry, Cell & Molecular Biology department at the University of Ghana, Accra. This five year programme led by Dr Gordon A. Awandare is funded by the Wellcome Trust to provide PhD and post-doctoral opportunities…
