The MRC have recently agreed to fund a three year project in the lab investigating human serum efficacy determinants in Trypanosoma brucei, specifically looking at intracellular transport and activation of the lytic factor(s). This will employ a similar approach to that used to identify the efficacy determinants of the five anti-HAT drugs published earlier this year (Alsford et al, 2012; see also Current Research).
I’ll be posting an advert soon for an experienced post-doc: someone with extensive cell and molecular biology skills, and a keen interest in host-parasite interactions. A detailed job description and person specification will be posted here and on the usual channels once I have them.